Process Automation and Robotics
A fully functioning overall system in YOUR pharmaceutical or biotechnolocial production process by Glatt Process & Plant Engineering.
Your factory of the future becomes reality with Glatt solutions.
Your production facility must be ONE system and not a series of individual machines. Challenge us as system integrator from A to Z from concept engineering up to fully system integration on site.
We ensure a fully functioning overall system.
In the fast-moving world of pharmaceutical and biotechnological production, automation and robotics are no longer optional – they’re essential. As a system integrator, we accompany you on the transition to the factory of the future. We specialize in integrating hardware and software functions into advanced holistic automation systems, which range from MES and DCS/SCADA systems to robot and AGV systems. We develop the best solution for your company and your project. Your process receives the suitable level of automation. Your company is thus equipped for the challenges of the future.
We support your production processes with:
- a high level of digitalization and automation from incoming raw materials to outgoing goods
- a consistent technical solution across all automation levels
- an optimal configuration of the systems and their interfaces
- an optimal interface between process and building automation systems
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Glatt as system integrator for the world’s first learning pharmaceutical production
We do not engineer machines, we create the system for your process.
Our range of services includes:
- automation and digitalization of process systems
- integrated design and execution
- integrated equipment management
- systems QR codes
- RFID technology for container monitoring
- assistance systems for operation and maintenance
- operator guidance and coordination
- assistance systems for production monitoring
- optimization of process sequences through the use of inline measurement technology.
This also includes the analysis and comparison of systems with regard to functionalities, properties, communication/interfaces, investment and operating costs.
Glatt robotics – the way from traditional production to automized production flow controlling
In addition to the automation of processes, our planning focuses on the digitalization and networking of processes and systems. We think from the customer’s perspective and support you right from the concept stage. You benefit from optimized and digitalized manufacturing and approval processes. Traditional manual activities, like batch reviews, are automated wherever possible. Time-consuming or error-prone processes are left to the robot systems. You reduce resources for routine activities. The production of very small batch sizes is cost-effective and paves the way towards individualized medicine.
Benefit from all these advantages for your factory of the future:
- high reproducibility of processes
- complete control of the processes, containers and therefore the input materials
- tracking of all sub-steps and containers
- automated review-by-exception
- shorter transfer times
- reduced space requirement
- humanless operation
- modularity and expandability in all areas
- cost-effective individualized medicine
Innovative Drum Handling Robot at the New Bayer Sol-1 Production Facility in Leverkusen, Germany
ISPE. RAYA 2023 Winner Audience Award
Cooperation of Bayer, Glatt, Hof and Stäubli
The objective of this robot application is to achieve a full automation of typically manual supported pharmaceutical production processes by combining common process equipment with robot arms!
Glatt in the collaborative project “ASTEROID-WS”
Automatic control and regulation online in the fluid bed
The aim of the joint project was the realization of a measurement and control system for monitoring and controlling the pharmaceutical manufacturing step “fluid bed granulation” on a pilot granulator. The automatic monitoring and control of the granulation process was to be developed on the basis of the direct product properties, since the granulation process defines the basis for important characteristics of the subsequent pharmaceutical form (uniformity of the active ingredient content, or processability in tabletting). In the course of this, the influence of the data recorded today on the quality of the intermediate product produced was to be examined. In addition, new possible parameters for process control were to be found and analyzed online. These could be, for example, the particle size distribution in the granules or a surface characteristic of the particles.
At the end of the project, methods were to be developed that would make it possible to monitor and control critical (relevant) process parameters in fluid bed granulation. In principle, this was intended to establish improved process control of granulation processes in the fluidized bed. Improved granules are to be produced through the targeted influencing of property distributions in fluid bed granulation. The already high quality level in pharmaceutical production would be further increased with the consequence of producing fewer deviations, having to block fewer batches and thus also improving quality and drug safety for the end user as well as conserving natural resources.
Project partners
- Bayer Weimar GmbH und Co. KG
- Glatt Ingenieurtechnik GmbH
- Forschungszentrum für Medizintechnik und Biotechnologie (fzmb) GmbH
- Leibniz-Institut für Photonische Technologien e.V. (IPHT)
Published article: Regulation and control systems for fluid bed spray agglomeration – Control models for every granule
(article in German language)
Follow a manual added link
Copyright: publish-industry Verlag GmbH
Fully automated processes require reliable process data. These are determined with methods of statistical experimental design and the application of artificial neural networks.
The presented case study has shown the potential as well as the general feasibility of a model-based control of a fluidized bed spray agglomeration process. In addition to the actual control task, the systematic approach allows a deeper insight into details of concrete industrial granulation processes. The process understanding gained in this way helps the respective users to gain insights into which additional possibilities exist for optimizing their granulation application. Nevertheless, close cooperation between the plant operator and the plant manufacturer is essential when designing a granulation plant. Only in this way can the full potential of the granulation process be exploited and the optimum solution developed for the user. Decades of experience in fluid bed granulation coupled with innovative plant and control concepts as well as process engineering solutions provide the right basis for this. (article in German language)
- Author: Dr.-Ing. Michael Jacob, Head of Operations Process Technology Feed, Food, Fine Chemicals, Glatt Ingenieurtechnik GmbH
- originally published in the trade magazine ‘P&A Prozessdigitalisierung Automation’, issue 10/2018, publish-industry Verlag GmbH
Further information on this topic and related topics can also be found in the following publications:
Link to: Glatt wins follow-up order for BioCampus MultiPilot
Copyright: ZVH Straubing
December 2023: Glatt wins follow-up order for BioCampus MultiPilot in the port of Straubing-Sand
Link to: Glatt selected for Engineering Project for new GMP Biorefinery by NSTDA in Thailand
August 2022: ‘Glatt selected for Engineering Project for new GMP Biorefinery by NSTDA in Thailand’
Link to: Topping-out ceremony for SOLIDA 1 at Bayer in Leverkusen, Germany
Copyright: Bayer AG
May 2022: Glatt as system integrator for the world’s first learning pharmaceutical production
Link to: High containment for solid drugsCopyright: Vogel Communications Group
Published article: ‘High Containment Processes in the Solid Drugs Production’ PDF, Englisch
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