Process Optimization
Glatt Process & Plant Engineering. We get the best out of YOUR pharmaceutical or biotechnolocial production process.
Glatt Process & Plant Engineering. We get the best out of YOUR pharmaceutical or biotechnolocial production process.
For optimal pharmaceutical or biotechnological production, precise process calculations and plant designs are just as crucial as process flow considerations and simulations for efficient plant planning. The same applies to logistical processes, efficient warehousing or questions of technical building equipment (HVAC, utilities) through to the degree of automation – to name but a few. Based on our planning approach, this is our understanding of process optimization.
We see process optimization as the challenge, knowledge of the solutions and possibilities as the necessary know-how and the available tools as aids for preparing and documenting decisions. We use commercially available tools, such as ChemCAD, or software developed in-house for process simulation. This enables us to determine the most efficient plant configurations and process parameters, among other things.
Digitalization in planning will become increasingly important in the future. We use BIM, e.g. REVIT, to record and visualize complex systems and data in a model to a meaningful extent, right up to the digital twin. We do not measure ourselves by the amount of data or the complexity of the model, but by the usability for the specific project requirements and the affordable level of detail. This approach makes digitalization meaningful and tangible and increases the acceptance of its use and further development.
Our own process simulation tool allows aasy access to all parameters via excel Data Input
Occupancy chart provided by our own process simulation tool. Shown here is an example for 2 product lines a) und b) with identical process steps. In product line b) equipment for buffer preparation, crystallization and filtration are shared for different process steps
Chart showing solids handling provided by our own process simulation tool. Example of 2 product lines; 1 line shifted for 1 hour in schedule (manpower)
Chart showing consumptions cooling water + hot water provided by our own process simulation tool. Example of 2 parallel lines; reduction of summarized utilities consumption peaks by time shift in occupancy chart (1 h)
Further information on this topic and related topics can also be found in the following publications:
December 2023: Glatt wins follow-up order for BioCampus MultiPilot in the port of Straubing-Sand
August 2022: ‘Glatt selected for Engineering Project for new GMP Biorefinery by NSTDA in Thailand’
Published article: ‘How to move biopharmaceuticals productions smoothly and quickly into Asian markets’ PDF, Englisch
Published article: ‘High Containment Processes in the Solid Drugs Production’ PDF, Englisch